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French club Bordeaux-Begles are the Champions Cup holders, after beating Northampton in last season's final in Cardiff
The 2025-26 Investec Champions Cup is set to get under way, with 12 pool matches to be played across 5-7 December.
Sale Sharks and Glasgow Warriors face each other in their opening Pool One fixture on Friday.
All of the team news and line-ups for the other eight games involving clubs from England, Scotland, Wales and Ireland can be found below.
Saracens v Clermont Auvergne
Venue: StoneX Stadium Date: Saturday, 6 December Kick-off: 13:00 GMT
Coverage: Full match commentary on BBC Radio London, with second half on BBC Radio 5 Sports Extra; live text updates on BBC Sport website and app
Saracens are without England internationals Maro Itoje, Jamie George and Ben Earl, as well as Argentina back row Juan Martin Gonzalez, as they begin their quest for a fourth European title.
Andy Onyeama-Christie returns to the starting line-up after missing last weekend's Prem defeat against Bath and there are two changes in the front row, where Marcus Street makes his first European start for the club and James Hadfield comes in at hooker for Theo Dan.
Nick Isiekwe starts alongside Hugh Tizard in the second row with Tom Willis at number eight.
The backline is unchanged from the Bath loss with scrum-half Ivan van Zyl captaining the side and Owen Farrell at 10.
Max Malins and the exciting Noah Caluori are on the wings with Champions Cup winner Elliot Daly at full-back.
Clermont, currently ninth in the French Top 14, make eight changes from their win over Stade Francais last weekend with seven players set to make their Champions Cup debuts. Experienced internationals Rob Simmons and George Moala start on the bench.
Saracens: Daly; Caluori, Cinti, Tompkins, Malins; Farrell, Van Zyl; Carre, Hadfield, Street, Isiekwe, Tizard, McFarland, Onyeama-Christie, Willis.
Replacements: Dan, Mawi, Riccioni, Wilson, Michelow, Bracken, Burke, Segun.
Clermont Auvergne: Guillaud; Tauzin, Newsome, Simone, Delguy; Plummer, Jauneau; Lotrian, Fourcade, Ojovan, Lanen, Ratuva, Chalus-Cercy, Hemery, Tolofua.
Replacements: Belkessa, Frisach, Dzmanashvili, Simmons, Michaux Vargas, Bezy, Moala, Dessaigne.
La Rochelle v Leicester
Venue: Stade Marcel Deflandre Date: Saturday, 6 December Kick-off: 17:30 GMT
Coverage: Commentary on BBC Radio Leicester and BBC Radio 5 Sports Extra; live text updates on BBC Sport website and app
Teenage full-back George Pearson replaces Freddie Steward as Leicester head coach Geoff Parling makes a number of changes from last week's win at Newcastle for the trip to two-time winners La Rochelle.
The 19-year-old England junior international is among several players making their Champions Cup debuts against Ronan O'Gara's side.
Hooker Charlie Clare captains as Leicester change their entire front row, with Nicky Smith, Jamie Blamire and Joe Heyes not in the matchday squad.
Hanro Liebenberg and Tommy Reffell also miss out with the back row made up of James Thompson, Joshua Manz and Joaquin Moro.
Billy Searle and Tom Whiteley make up the half-backs with Adam Radwan and Ollie Hassell-Collins keeping their places on the wings.
La Rochelle, currently 10th in the French Top 14, are captained by France international Gregory Alldritt, who is joined by Levani Botia and Oscar Jegou in the back row.
They are without several key players through injury such as Will Skelton, Jonathan Danty, Nolann le Garrec and England winger Jack Nowell. Uini Atonio and Irishman Ultan Dillane are on the bench.
La Rochelle: Leyds; Niniashvili, Seguret, Seuteni, Favre; West, Berjon; Kaddouri, Latu, Sclavi, Lavault, Kante Samba, Jegou, Botia, Alldritt.
Replacements: Lespiaucq, Wardi, Atonio, Dillane, Andjisseramatchi, Couillaud, Jurd, Bollengier.
Leicester Tigers: Pearson; Radwan, Wand, Woodward, Hassell-Collins; Searle, Whiteley; Haffar, Clare, Hurd, Henderson, Wells, Thompson, J Manz, Moro.
Replacements: Theobald-Thomas, Van der Flier, Loman, T Manz, Williams, Allan, Titcombe, Kata.
Leinster v Harlequins
Venue: Aviva Stadium Date: Saturday, 6 December Kick-off: 17:30 GMT
Coverage: Live text updates on BBC Sport website and app
New Zealand international Rieko Ioane is set to make his Leinster debut off the bench against Harlequins.
Caelan Doris captains the side in his first Leinster appearance since May and is joined in the back row by Jack Conan and Josh van der Flier, while Joe McCarthy partners South Africa international RG Snyman in the second row.
Ireland trio Thomas Clarkson, Dan Sheehan and Paddy McCarthy are named in the front row, with the latter making his Champions Cup debut.
Sam Prendergast and Jamison Gibson-Park are paired in the half-backs, while Jordan Larmour, Tommy O'Brien and Jimmy O'Brien make up the back three.
Andrew Porter, James Lowe and Robbie Henshaw are not included.
Cadan Murley captains Harlequins against the four-time winners with Argentina international Boris Wenger making his first start at loose-head prop alongside Jack Walker and the returning Harry Williams in the front row.
England internationals Marcus Smith, Fin Baxter and Chandler Cunningham-South are unavailable because of a mandatory rest period after the autumn series, with Alex Dombrandt and Tyrone Green on the injury list.
Will Porter continues at scrum-half with Wales international Jarrod Evans at fly-half. Luke Northmore returns at inside centre with Oscar Beard outside him and Cameron Anderson at full-back.
Leinster: J O'Brien; T O'Brien, Ringrose, Frawley, Larmour; Prendergast, Gibson-Park; P McCarthy, Sheehan, Clarkson, Snyman, J McCarthy, Conan, Van der Flier, Doris.
Replacements: Kelleher, Boyle, Furlong, Mangan, Deegan, McGrath, Byrne, Ioane.
Harlequins: Anderson; Cleaves, Beard, Northmore, Murley; Evans, Porter; Wenger, Walker, Williams, Treadwell, Lewies, Carr, Evans, Lawday.
Replacements: Turner, Hobson, Delgado, Launchbury, Schmid, Friday, Benson, Bradley.
Bath v Munster
Venue: The Rec Date: Saturday, 6 December Kick-off: 20:00 GMT
Coverage: Commentary on BBC Radio Somerset and BBC Radio 5 Sports Extra; live text updates on BBC Sport website and app
Finn Russell will make his 50th appearance for Prem champions Bath as they set their sights on a first Champions Cup trophy since 1998.
The one-time winners will certainly aim to better their disappointing group-stage exit last season and have named a strong side captained by Ben Spencer for the sell-out game at the Rec.
Beno Obano, Tom Dunn and Will Stuart start in the front row with England's Guy Pepper returning to the starting line-up at open-side flanker.
Cam Redpath and Max Ojomoh form the centre partnership with Henry Arundell and Joe Cokanasiga on the wings and Tom de Glanville at full-back.
Ted Hill, Sam Underhill and Santi Carreras are among the replacements.
Munster will be without fly-half Jack Crowley who has been ruled out with a leg injury as head coach Clayton McMillan makes five changes from the side that lost to the Stormers last weekend.
Ex-Leinster prop Michael Ala'alatoa is set for his Munster debut off the bench, while JJ Hanrahan comes in to replace Crowley and partners Craig Casey in the half-backs.
Jean Kleyn returns from international duty with South Africa to start in the pack, with captain Tadhg Beirne, John Hodnett and Gavin Coombes in the back row.
Bath: De Glanville; Cokanasiga, Ojomoh, Redpath, Arundell; Russell, Spencer; Obano, Dunn, Stuart, Roux, Ewels, Bayliss, Pepper, Reid.
Replacements: Tuipulotu, Van Wyk, Du Toit, Molony, Hill, Carr-Smith, Carreras, Underhill.
Munster: Daly; Kilgallen, Farrell, Kelly, Abrahams; Hanrahan, Casey; Milne, Barron, Ryan, Kleyn, Ahern, Beirne, Hodnett, Coombes.
Replacements: Barron, Loughman, Ala'alatoa, Edogbo, Quinn, Coughlan, Nankivell, Kendellen.
Scarlets v Bristol
Venue: Parc y Scarlets Date: Saturday, 6 December Kick-off: 20:00 GMT
Coverage: Commentary on BBC Radio Wales, BBC Radio Bristol and BBC Radio 5 Sports Extra 2; live text updates on BBC Sport website and app
Ellis Genge returns to the Bristol starting 15 and Gabriel Oghre makes his 50th appearance for the Bears as they begin their Champions Cup campaign at Parc y Scarlets.
Louis Rees-Zammit comes into the team in place of the injured Jack Bates and Max Lahiff starts ahead of Jake Woolmore as Pat Lam largely sticks with the side that beat Northampton 46-12 last Saturday.
Fly-half Sam Worsley continues at fly-half and Fitz Harding captains the team for a record sixth time in Champions Cup games.
Young Welsh winger Aidan Boshoff is set for his Champions Cup debut off the bench after scoring his first Prem try last weekend.
Scarlets head coach Dwayne Peel makes three changes to the team that beat Glasgow 23-0 last weekend with Wales internationals Tom Rogers, Johnny Williams and Ellis Mee coming into the backline.
The region are without full-back Blair Murray, who started all four of Wales' autumn internationals, because of a knock.
Taine Plumtree misses out with a rib injury while Joe Hawkins and Joe Roberts are on the bench after featuring against South Africa last weekend.
Scarlets: J Davies; Rogers, James, Williams, Mee; Costelow, G Davies; Mathias, Elias, Holz, Lousi, Ball, Douglas, Macleod, Anderson.
Replacements: Van der Merwe, O'Connor, Thomas, Taylor, Davis, Blacker, Hawkins, Roberts.
Bristol: Jordan; Rees-Zammit, Van Rensburg, Williams, Ravouvou; Worsley, Marmion; Genge, Oghre, Lahiff, Rubiolo, Batley, Grondona, Harding, Mata.
Replacements: Thacker, Woolmore, Chawatama, Owen, Grondona, Wolstenholme, Boshoff, Carrington.
Pau v Northampton
Venue: Stade du Hameau Date: Sunday, 7 December Kick-off: 13:00 GMT
Coverage: Commentary on BBC Radio Northampton and BBC Radio 5 Sports Extra 3; live text updates on BBC Sport website and app
Gloucester v Castres
Venue: Kingsholm Date: Sunday, 7 December Kick-off: 15:15 GMT
Coverage: Commentary on BBC Radio Gloucestershire and BBC Radio 5 Sports Extra 2; live text updates on BBC Sport website and app
Edinburgh v Toulon
Venue: Hive Stadium Date: Sunday, 7 December Kick-off: 17:30 GMT
Coverage: Live text updates on BBC Sport website and app

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